Today’s Federal Register carries a notice from the National Institute for Occupational Health and Safety (NIOSH) requesting information and comments regarding silver nanoparticles. NIOSH

has initiated an evaluation of the scientific data on silver nanoparticles (AgNPs) to ascertain the potential health risks to workers and to identify gaps in knowledge so that appropriate laboratory and field research studies can be conducted. . . .

. . . gathering data to determine whether a health risk to workers may exist from exposure to AgNPs and if specific risk management guidance is needed to prevent exposure. . . .  

Information is particularly needed for determining the relevance of bile duct hyperplasia and hepatocellular necrosis observed in AgNP exposed rats, as well as information on: (1) Sources of AgNP exposure, (2) factors that influence worker’s exposure, (3) in-place exposure control measures (e.g., engineering controls) and work practices that are effective in reducing worker exposures, and (4) appropriate measurement methods and exposure metrics for characterizing workplace exposures. . . .

Examples of requested information include the following:     (1) Identification of industries or occupations in which exposures to AgNPs may occur.     (2) Trends in the production and use of AgNPs.     (3) Description of work tasks and scenarios with a potential for exposure to AgNPs.     (4) Workplace exposure measurement data in various types of industries and jobs.     (5) Case reports or other health information demonstrating potential health effects in workers exposed to AgNPs.     (6) Research findings from in vitro and …