NumaDerm is a new line of skin care products manufactured by in Scottsdale, Arizona. The product claims to subcutaneously deliver proprietary blend of bioactive compounds and other ingredients deep beneath the skin’s surface into individual cells. claims its nanospheres "are small enough to penetrate the skin’s surface" in order to deliver their active ingredients. Luckily the nanospheres that encapsulate the ingredients are biodegradable "food grade" compounds that minimize toxicity.

Evidently the folks at are unaware of the tremendous efforts the Cosmetic, Toiletry, and Fragrance Association and mainline companies such as L’Oreal have made trying to convince the FDA and the general public that nanoscale materials do not penetrate beneath the stratum corneum — and certainly not down into subcutaneous skin layers.